Publications

Selected Publications.

For a complete list of publications, please see PubMed.

Capdevila, C., Miller, J., Cheng, L., Kornberg, A., George, J. J., Lee, H., Botella, T., Moon, C. S., Murray, J. W., Lam, S., Calderon, R. I., Malagola, E., Whelan, G., Lin, C. S., Han, A., Wang, T. C., Sims, P. A., & Yan, K. S. (2024). Time-resolved fate mapping identifies the intestinal upper crypt zone as an origin of Lgr5+ crypt base columnar cells. Cell, 187(12), 3039–3055.e14. https://doi.org/10.1016/j.cell.2024.05.001

Kornberg, A., Botella, T., Moon, C. S., Rao, S., Gelbs, J., Cheng, L., Miller, J., Bacarella, A. M., García-Vilas, J. A., Vargas, J., Yu, X., Krupska, I., Bush, E., Garcia-Carrasquillo, R., Lebwohl, B., Krishnareddy, S., Lewis, S., Green, P. H. R., Bhagat, G., Yan, K. S., … Han, A. (2023). Gluten induces rapid reprogramming of natural memory αβ and γδ intraepithelial T cells to induce cytotoxicity in celiac disease. Science immunology, 8(85), eadf4312. https://doi.org/10.1126/sciimmunol.adf4312

Monnot, G. C., Wegrecki, M., Cheng, T. Y., Chen, Y. L., Sallee, B. N., Chakravarthy, R., Karantza, I. M., Tin, S. Y., Khaleel, A. E., Monga, I., Uwakwe, L. N., Tillman, A., Cheng, B., Youssef, S., Ng, S. W., Shahine, A., Garcia-Vilas, J. A., Uhlemann, A. C., Bordone, L. A., Han, A., Rohde, C.H., Ogg, G., Moody, D.B., Rossjohn, J. and de Jong, A. (2023). Staphylococcal phosphatidylglycerol antigens activate human T cells via CD1a. Nature Immunology 24: 110–122. https://doi.org/10.1038/s41590-022-01375-z

Reis, B.S., Darcy, P.W., Khan, I.Z., Moon, C.S., Kornberg, A.E., Schneider, V.S., Alvarez, Y., Eleso, O., Zhu, C., Schernthanner, M., Lockhart, A., Reed, A., Bortolatto, J., Castro, T.B.R., Bilate, A.M., Grivennikov, S., Han, A.S. and Mucida, D. (2022) TCR-Vγδ usage distinguishes protumor from antitumor intestinal γδ T cell subsets. Science 377: 276–284. https://doi.org/10.1126/science.abj8695

Masuda, K., Kornberg, A., Miller, J., Lin, S., Suek, N., Botella, T., Secener, K.A., Bacarella, A.M., Cheng, L., Ingham, M., Rosario, V., Al-Mazrou, A.M., Lee-Kong, S.A., Kiran, R.P., Stoeckius, M., Smibert, P., Del Portillo, A., Oberstein, P.E., Sims, P.A., Yan, K.S. and Han, A. (2022) Multiplexed single-cell analysis reveals prognostic and nonprognostic T cell types in human colorectal cancer. JCI Insight 7: e154646. https://doi.org/10.1172/jci.insight.154646

Habal, M.V., Miller, A.M.I., Rao, S., Lin, S., Obradovic, A., Khosravi-Maharlooei, M., See, S.B., Roy, P., Shihab, R., Ho, S.H., Marboe, C. C., Naka, Y., Takeda, K., Restaino, S., Han, A., Mancini, D., Givertz, M., Madsen, J.C., Sykes, M., Addonizio, L.J., Farr, M.A. and Zorn, E. (2021) T cell repertoire analysis suggests a prominent bystander response in human cardiac allograft vasculopathy. Am. J. Transplant. 21: 1465–1476. https://doi.org/10.1111/ajt.16333

Li, Y., Teteloshvili, N., Tan, S., Rao, S., Han, A., Yang, Y. G., & Creusot, R. J. (2019). Humanized mice reveal new insights into the thymic selection of human autoreactive CD8+ T cells. Frontiers in Immunology 10: 63. https://doi.org/10.3389/fimmu.2019.00063

Gee, M.H.*, Han, A.*, Lofgren, S.M., Beausang, J.F., Mendoza, J.L., Birnbaum, M.E., Bethune, M.T., Fischer, S., Yang, X., Gomez-Eerland, R., Bingham, D.B., Sibener, L.V., Fernandes, R.A., Velasco, A., Baltimore, D., Schumacher, T.N., Khatri, P., Quake, S.R. and Davis, M.M. (2017) Antigen identification for orphan T cell receptors expressed on tumor-infiltrating lymphocytes. Cell 172: 549–563.e16. https://doi.org/10.1016/j.cell.2017.11.043 *equal contribution

Hansmann, L., Han, A., Penter, L., Liedtke, M. and Davis, M.M. (2017) Clonal expansion and interrelatedness of distinct B-lineage compartments in multiple myeloma bone marrow. Cancer Immunol Res. 5: 744-754.

Yan, K.S., Gevaert, O., Zheng, G.X.Y., Anchang, B., Probert, C.S., Larkin, K.A., Davies, P.S., Cheng, Z.F., Kaddis, J.S., Han, A., Roelf, K., Calderon, R.I., Cynn, E., Hu, X., Mandleywala, K., Wilhelmy, J., Grimes, S.M., Corney, D.C., Boutet, S.C., Terry, J.M., Belgrader, P., Ziraldo, S.B., Mikkelsen, T.S., Wang, F., von Furstenberg, R.J., Smith, N.R., Chandrakesan, P., May, R., Chrissy, M.A.S., Jain, R., Cartwright, C.A., Niland, J.C., Hong, Y.K., Carrington, J., Breault, D.T., Epstein, J., Houchen, C.W., Lynch, J.P., Martin, M.G., Plevritis, S.K., Curtis, C., Ji, H.P., Li, L., Henning, S.J., Wong, M.H. and Kuo, C.J. (2017) Intestinal enteroendocrine lineage cells possess homeostatic and injury-inducible stem cell activity. Cell Stem Cell. 21: 78-90.

Glanville, J., Huang, H., Nau, A., Hatton, O., Wagar, L.E., Rubelt, F., Ji, X., Han, A., Krams, S.M., Pettus, C., Haas, N., Arlehamn, C.S.L., Sette, A., Boyd, S.D., Scriba, T.J., Martinez, O.M. and Davis, M.M. (2017) Identifying specificity groups in the T cell receptor repertoire. Nature 547:94-98.

Yan, K.S., Janda, C.Y., Chang, J., Zheng, G.X.Y., Larkin, K.A., Luca, V.C., Chia, L.A., Mah, A.T., Han, A., Terry, J.M., Ootani, A., Roelf, K., Lee, M., Yuan, J., Li, X., Bolen, C.R., Wilhelmy, J., Davies, P.S., Ueno, H., von Furstenberg, R.J., Belgrader, P., Ziraldo, S.B., Ordonez, H., Henning, S.J., Wong, M.H., Snyder, M.P., Weissman, I.L., Hsueh, A.J., Mikkelsen, T.S., Garcia, K.C. and Kuo, C.J. (2017) Non-equivalence of Wnt and R-spondin ligands during Lgr5+ intestinal stem-cell self-renewal. Nature 545: 238-242.

Han, A., Glanville, J., Hansmann, L. and Davis, M.M. (2015) Corrigendum: Linking T-cell receptor sequence to functional phenotype at the single-cell level. Nature Biotechnol. 33: 210

Wei, Y.L., Han, A., Glanville, J., Fang, F., Zuniga, L.A., Lee, J.S., Cua, D.J. and Chien, Y.H. (2015) A highly focused antigen receptor repertoire characterizes gamma delta T cells that are poised to make IL-17 rapidly in naive animals. Frontiers in Immunology 6: 118.

Han, A., Glanville, J., Hansmann, L. and Davis, M.M. (2014) Linking T-cell receptor sequence to functional phenotype at the single-cell level. Nature Biotechnology 32: 684-692.

Han, A., Newell, E.W., Glanville, J., Fernandez-Becker, N., Khosla, C., Chien, Y.H. and Davis, M.M. (2013) Dietary gluten triggers concomitant activation of CD4+ and CD8+ alpha beta T cells and gamma delta T cells in celiac disease. Proc. Natl. Acad. Sci. U.S.A. 110: 13073-13078.

Su, L.F., Kidd, B.A., Han, A., Kotzin, J.J. and Davis, M.M. (2013) Virus-specific CD4(+) memory-phenotype T cells are abundant in unexposed adults. Immunity 38: 373-383.

Su, L.F., Han, A., McGuire, H.M., Furman, D., Newell, E.W. and Davis, M.M. (2013) The promised land of human immunology. Cold Spring Harbor Symp. on Quant. Bio. 78: 203-213.

Yan, K.S., Yan, S., Farooq, A., Han, A., Zeng, L. and Zhou, M.M. (2003) Structure and conserved RNA binding of the PAZ domain. Nature 426: 468-474.

Han, A., Saijo, K., Mecklenbräuker, I., Tarakhovsky, A. and Nussenzweig, M.C. (2003) Bam32 links the B cell receptor to ERK and JNK and mediates B cell proliferation but not survival. Immunity 19: 621-632.